Yes, the CoolStream CarPro for BMW will work with the Infiniti 2008 E53. But you need to use an additional power charge adapter. The cable from Infiniti lacks the power to charge an iPod or power on the CarPro.
The CarPro connects to the charge adapter.
The charge adapter is connected to both the 30 pin connector on the Infiniti MMI cable and to the Infiniti 2008 E35 lighter socket by a micro USB cable. The CoolStream CarPro then goes on top of the charge adapter. Using the CarPro and power charge adapter together, you will be able to stream music from your iPhone or Android to the Infiniti 2008 E35 speakers.

The CarPro works with the music controls on the steering wheel of the Infiniti. The CarPro will also display the music that you have downloaded and saved on your iPhone.

CoolStream can report that the Infiniti 2008 E35, 2009 E35, 2008 G35, 2008 G37, 2009 FX35, 2011 M45 have underpowered MMI cables and will only work with the CarPro and an additional Charge Adapter.
If you own one of the vehicles listed above we recommend the CoolStream CarPro Bluetooth Kit for Infiniti, Nissan, and Volvo.